For the past month I’ve been mostly immersed in developing and testing a whole genome metagenomics workflow for the core, and I’ve noticed that available…
I had the great privilege of attending the Intelligent Systems for Molecular Biology conference in Madison, July 10–14. Here, I’m sharing about something interesting I…
Most people are familiar with the idea of the microbiome – the communities of microbes that populate just about everything, from soil to air conditioning…
A heatmap is one of the most effective ways to quickly visualize the differences between RNA sequencing samples on a broad scale – and is…
Next Generation Sequencing After the human genome was painstakingly sequenced using capillary electrophoresis, it was obvious that incredible scientific potential was present within the genetic…
Telomeres are a fascinating and essential aspect of linear chromosomal DNA, protecting the ends of the chromosomes from entanglement with other nuclear molecules and from…
Originally published in 2010 and cited an astounding >27K times as of this month, the edgeR package (Robinson, McCarthy, and Smyth, 2010) is a reliable…
One of the central assumptions of genetic inheritance is that only a mutation in a germline cell (e.g., a sperm or egg cell) can be…
Individual StringTie Quants After aligning your RNA-seq samples to a reference genome with STAR (see our two-part STAR tutorial here and here), the alignment data…
I had the great privilege of attending the Intelligent Systems for Molecular Biology conference in Madison, July 10–14. Here, I’m sharing about something interesting I…